Cataracts tend to “grow” slowly, so vision gets worse gradually. Environmental factors, including toxins, radiation, and ultraviolet light, have cumulative effects, which are worsened by the loss of protective and restorative mechanisms due to alterations in gene expression and chemical processes within the eye. 12 Blunt trauma causes swelling, thickening, and whitening of the lens fibbers. This type of cataract can present with a shift to near-sightedness and causes problems with distance vision, while reading is less affected. 30 Cortical cataracts are due to the lens cortex outer layer becoming opaque. Then your doctor will determine how much eyesight has improved before surgery is done on the second eye. How soon will my vision improve? The extent of the visual disturbance is dependent upon the degree of cloudiness of the lens. In a normal eye, light passes through the transparent lens to the retina. Cataract surgery for clearer vision When a cataract causes bothersome vision problems that interfere with your daily activities, your ophthalmologist may recommend surgery to remove the cataract. Archives of Ophthalmology. 2010;128:738. Frequent prescription changes in your eyeglasses or contact lenses.
Shruti Sharma of the Center for Biotechnology and Genomic Medicine has a $1.5 million grant from the National Eye Institute to look at basic research into blocking inflammation among epithelial cells in light-sensing retina in the eye, Sharma is looking at a well-known agent in inflammation called interleukin-6 that can affect those cells even though they lack the receptor normally needed for such interaction, an effect called trans-signaling. While that effect had been known for a while it is not something that researchers had focused on in the past, she said. Sharma is looking at an experimental drug that in her early work seems to have blocked that type of action in those cells, using it both in the lab in human cells in the same kind of environment that is there in the eye and in a mouse model of diabetes. The hope is to prevent the barrier disruption to the cells that can cause them to become leaky and create inflammation, an early hallmark of the disease. The mouse model allows Sharma to test the compound in both late and early stages of the disease to see if it she can prevent diabetic retinopathy from happening, she said. Separately, the compound is being tested in human clinical trials in rheumatoid arthritis, which is also promising, Sharma said. Im more excited because I am re-purposing this drug, she said. I am not trying to develop a new drug. But that potential is why Augusta University has translational programs to try and bring those promising research ideas to the clinic, said Nussbaum , chair of the Department of Ophthalmology. http://dclakers.com/advisingeyesurgeon/2016/12/05/a-closer-look-at-strategies-of-cataracts/And it is a big problem to address – there are at least 4.2 million people with diabetic retinopathy in the U.S., according to the American Diabetes Association. Diabetes affected 9.1 percent of people in the U.S.
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June 11, 2013. Your Questions about Cataract Surgery Answered – Videos 11 Michael Smith-Wheelock, M.D., comprehensive ophthalmologist and cataract surgeon, answers the most commonly asked questions about cataract surgery. shied Dr., MD, face, face William C. A posterior sub capsular cataract starts as a small, opaque area that usually forms near the back of the lens, right in the path of light on its way to the retina. A cortical cataract is characterized by white, wedge-like opacities that start in the periphery of the lens and work their way to the canter in a spoke-like fashion. In a normal eye, light passes through the transparent lens to the retina. The protein is arranged in a precise way that keeps the lens clear and lets light pass through it. Phacoemulsification typically comprises six steps: Anaesthetic – The eye is numbed with either a sub tenon injection around the eye or using simple eye drops. Is cataract surgery effective? If you have any questions or concerns about cataract surgery, be sure to discuss them with your eye doctor and cataract surgeon prior to signing “informed consent” documents authorizing surgery. no data